GELATIN IN CAPSULES - HOW DOES GELATIN IN HARD CAPSULES DIFFER FROM SOFT CAPSULES?

Gelatin in Capsules – How Do Hard Capsules Differ from Soft Capsules?

Gelatin is a widely used material in the pharmaceutical capsule industry, valued for its safety and excellent molding properties. But did you know that gelatin used in hard capsules and soft capsules has significant differences? This article will help you understand each type, from composition and production processes to practical applications.

Gelatin in Hard Capsules

Hard capsules, also known as two-piece capsules, are the most common type in the pharmaceutical field. They typically contain powdered, granulated, or pelletized medications.

1. Composition
Gelatin for hard capsules is usually made from:

• Animal gelatin: Derived from bovine or porcine skin and bones.
• Additives: Including water, coloring agents, and preservatives (if needed).

This type of gelatin has a high bloom strength (200-250), providing elasticity while maintaining a suitable hardness for the capsule.

2. Production Process

• Gelatin is dissolved in hot water to create a solution.
• The solution is dipped onto molds to form the two halves of the capsule.
• The capsules are dried, trimmed, and assembled.

3. Applications
Hard capsules are ideal for packaging heat-sensitive and moisture-absorbing drugs. They are also cost-effective and commonly used for probiotics, vitamins, and prescription drugs.

Gelatin in Soft Capsules

Soft capsules are single-piece capsules, typically containing active ingredients in liquid or gel form.

1. Composition
Gelatin for soft capsules is combined with additional components:

• Plasticizers: Such as glycerin or sorbitol, to create flexibility.
• Preservatives: To extend the product’s shelf life.

This gelatin has a lower bloom strength (150-200), making it suitable for a soft yet durable structure.

2. Production Process
The production of soft capsules requires more advanced technology:

• Liquid gelatin is poured into molds and shaped.
• Active ingredients are injected while the gelatin is still soft.
• Capsules are sealed and dried to complete the process.

3. Applications
Soft capsules are best suited for oil-based or gel-like active ingredients. Common products include fish oil capsules, vitamin A and D supplements, and some pain relievers.

Comparison Between Gelatin in Hard and Soft Capsules

Conclusion

Gelatin is an indispensable material in capsule manufacturing, and each capsule type is optimized for specific purposes. Hard capsules are suitable for powdered medications, while soft capsules excel in preserving oil-based solutions. Differences in composition and production processes highlight the unique advantages of each type.

When selecting the appropriate capsule type, consider practical usage needs and the characteristics of the pharmaceutical product to ensure maximum safety and efficiency.

ABOUT GREENIFI GELATINE: 

We proudly supply bovine gelatine powder with bloom strength ranging from 100 to 250 and mesh size from 8 to 20, entirely produced in Vietnam. Greenifi Gelatine products meet all international certifications, including GMP, FDA, ISO 22000:2018, and come with a COA adhering to the Vietnamese Pharmacopoeia standards, ensuring exceptional safety and quality.

Comprehensive Support:

• Proper gelatine usage: Avoid issues like clumping or failure to set during production.

• Addressing common challenges: Solutions for soft capsules, gummy candies, and cosmetic gels.

• Distinguishing gelatin types: Understand the differences between gelatine sheets and powder.

• Technical specifications: Grasp the importance of bloom strength, mesh size, and other critical parameters.

• Exploring applications: Learn about gelatine's benefits and the risks of incorrect usage.

📩 Contact us:

• Email: info@global-ifi.com

• Facebook: www.facebook.com/greenifigelatin

Greenifi Gelatin - Green ingredients for good life!